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Yamada H, Takuma N, Daimon T, Hara Y

Studies with liraglutide have shown mixed results, with some suggesting potential benefits alongside modest motor effects, though robust evidence for cognitive improvements is currently lacking

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Available at: [accessed March 2026]. Phase 3 ESSENCE trial: Semaglutide in metabolic dysfunctionassociated steatohepatitis secondary analyses

Semaglutide works by slowing stomach emptying and signaling fullness to the brain, yet some patients report weight gain or plateaus after initial success