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Most are gastrointestinal and usually improve with time
Both classes of medications are still considered to be valuable therapies for diabetes management and cardiovascular protection
Side effects can include dizziness, drowsiness, nausea, and vomiting
When walking, climbing stairs, or standing for extended periods becomes difficult, many experience significant stress managing their condition, while others suffer in silence
The hydrophobic face of GLP-1, formed by the conserved residues Phe 22 , Ile/Val 23 , Trp 25 , and Leu 26 , is responsible for interacting with the hydrophobic binding pocket in the ECD of GLP1R [37]
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