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Unlike GSH, which can be unstable in plasma, S-Acetyl-L-glutathione's unique acetylation at the sulfur atom not only prevents its decomposition but also enhances its absorption through the intestinal wall
The step-wise dose increases exist to manage GI adaptation
10.1073/pnas.0510033103 136 SpieringB.KraemerW.AndersonJ.ArmstrongL.NindlB.VolekJ.et al
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