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Mehta A, Mason P, Vulliamy T
It activates the sirtuin family of enzymes, which regulate DNA repair and cellular maintenance
Expanding the phenotypic spectrum of BCS1L-related mitochondrial disease
Combination of IGF-IR inhibitor and these chemotherapeutic agents may result in increased DNA double strand breaks, apoptosis, and mitotic catastrophe
It is also being promoted as a systemic skin-whitening agent probably related to its antiplasmin activity
PMID 25753888
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