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Sun Exposure - Too much exposure to the UV rays causes darkening of lips if you don't follow sun protection or at least apply spf Biting of Lips - Constantly biting or licking lips can also cause discoloration and irritation

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The rate at which each gene was mentioned was assumed to be associated with the likelihood that it was correlated with G6PD, and the number of articles in which a given gene was associated with G6PD (k) was recorded