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In brief, heart tissue was homogenized in ice-cold 6% perchloric acid, centrifuged at 1000 rpm for 15 min at 0.5 C, and the supernatant fluid was injected into HPLC after neutralization to pH 67
This is one reason why supporting our antioxidant pathways becomes more important as the years pass
The inconsistency of the above results may be because the duration of myocardial ischemia in the latter was too short to induce ferroptosis
10.1007/s40588-018-0081-2 124 LorenzenI.MullenL.BekeschusS.HanschmannE
Sakamoto T, Batmanov K, Wan S, Guo Y, Lai L, Vega RB, et al
Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a tethering mechanism: a two-site interaction model for the Nrf2-Keap1 complex
