PloS one, 11(1), e0147056
Ascorbate can be regenerated from its oxidized forms, monodehydroascorbate (MDHA) and dehydroascorbate (DHA), by MDHA and DHA reductases (MDHARs and DHARs), respectively (Smirnoff, 2018) The activity of DHARs is coupled to oxidation of glutathione, which is also required for spontaneous, non-enzymatic reduction of DHA to ascorbate (Figure 1)
2017;66:921.e7
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Additionally, it minimizes the appearance of large pores and strengthens the skin barrier, making your skin less reactive to acne-triggering pollutants
This modification, although behind the scenes, triggers necessity for Highmark to make system changes and issue notifications to impacted clients