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Long-term treatment must be considered in addition to short-term medicines, taking into account the potential consequences of the artificial tears, anti-inflammatory eye drops, and punctal plugs are examples of conventional treatments for dry eye disease that can be successful, but long-term use can be costly and may result in adverse effects that limit patient adherence [38, 39]
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Those with objective evidence of disease control (normal fecal calprotectin, endoscopic remission) may be better candidates than those with frequent flares or active inflammation
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