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Vitamin E may also play a role in reducing the risk of heart disease (important for women with PCOS).Oxidative stress is a major concern for women who are trying to conceive and have either insulin resistant, PCOS or diabetes
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The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory
