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P62/SQSTM1, the most studied autophagy receptor, binds to autophagic membranes through its LIR or GIM structural domains, to the proteasome through its Phox and Bem1p structural domains (PB1), and to ubiquitinated substrates through its Ub-associated structural domain (UBA)
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Glutathione is the only intracellular antioxidant found, which means it acts inside the cells