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Direct hGH is increasingly reserved only for severe cases of documented adult growth hormone deficiency (AGHD) that fail to respond to secretagogues

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To date, about 7,000 naturally occurring peptides have been identified

Anselmo AC, Mitragotri S (2016) Nanoparticles in the clinic

The peptides sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) was first characterized by research groups investigating cytoprotective properties of gastric juice-derived compounds