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Step two: adding injectable therapy When metformin alone (or metformin plus other oral agents) fails to achieve blood sugar targets, the next decision is whether to add a GLP-1 agonist or insulin

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This encompassed articles, reviews, and clinical studies available in databases such as PubMed, MEDLINE, and Google Scholar

While this change may appear modest, even small reductions in systolic blood pressure are associated with meaningful decreases in cardiovascular risk at the population level