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Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria
doi: 10.5114/aoms.2016.61789 178 LiuGLvYWangYXuZChenLChenSet al
Vannier and G
A meta-analysis of randomized controlled trials found that daily vitamin E supplementation equivalent to 25 to 536 mg/day of RRR --tocopherol for several years resulted in a significant, 10% reduction in the risk of ischemic stroke (five trials, 91,393 participants) and a nonsignificant trend towards an increased risk of hemorrhagic stroke (five trials, 100,748 participants) (120)
Montagner, A., et al
For instance, exposure to H 2 O 2 stimulates PARP1 activation and subsequent AIFM1 nuclear translocation in glioma cells [156]
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