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Herlev og Gentofte Hospital Steno Diabetes Center Copenhagen Department of Biomedical Sciences Mats Christian Hjbjerg Lassen, MD To view or add a comment, sign in Moderate-to-Vigorous Physical Activity and Cardiovascular Outcomes in Genotype-Positive, Phenotype-Negative Cardiomyopathy Carriers In a large prospective cohort from the UK Biobank including 84,699 individuals, of whom 3,979 were genotype-positive and phenotype-negative (G+P) carriers of cardiomyopathy-associated variants, objectively measured moderate-to-vigorous physical activity (MVPA) was consistently associated with meaningful cardiovascular benefit

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Cardiomyopathy can develop in the absence of an acute episode, and can result in death

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The absence of expected appetite suppression does not necessarily indicate treatment failure , but it does warrant careful evaluation