[1] It is administered as a once-weekly subcutaneous injection and belongs to a novel class of medications known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists
The intake also includes a direct self-harm question, a black-box family-history screen covering MTC, MEN2, pancreatitis, gastroparesis, and Long QT, and a family-history question about sudden cardiac death under age 40
Based on Phase 2 studies, the initial dose may begin at 1 mg to 2 mg (0.0750.15 mL) once weekly, with gradual titration every 4 weeks in increments of 2 mg to 4 mg, as tolerated, up to a maximum of 12 mg (0.90 mL) weekly Doses between 4 mg and 12 mg weekly demonstrated meaningful reductions in body weight and glycemic parameters over 16 to 28 weeks
Strange et al., 2000)
High-purity metabolic research compound, precisely dosed and tested for consistency
Switching rates were highest in January 2023 (around 3% for the study population regardless of the presence of type 2 diabetes (T2D) or overweight/obesity)