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2 Methods 2.1 Literature search PubMed, Web of Science, CNKI, Wanfang, and VIP databases were searched, using keywords such as ferroptosis, cancer, traditional Chinese medicine and polysaccharide to retrieve studies on the therapeutic potential of plant polysaccharides in cancer treatment targeting ferroptosis
Immune-cell activation can reorganize nutrient use, NADPH production, mitochondrial metabolism, and thiol-dependent signaling, making glutathione regulation one component of broader immunometabolic control
Endotoxin exposure can also contribute to the development of chronic diseases such as metabolic syndrome, diabetes, and cardiovascular disease
Similar content being viewed by others Introduction Biological thiols, including glutathione (GSH), cysteine (Cys) and homocysteine (Hcy), play a pivotal role in many biological processes such as regulating redox homeostasis, detoxification and metabolism and as an active site of enzymes and cofactors 1,2
Hunter, E
(14) More research needs to be done on the relationship between inflammation and glutathione, but it gives us a clearer starting point in treating these conditions
