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CS is frequently used in the creation of innovative nanotherapeutic drugs for asthma because of its suitability with airway epithelial cells, excellent mucoadhesion, penetration-improvement capabilities, and antibacterial activities [54]

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CF is associated with significant alterations to the gut microbiome, and CF patients are more at risk of developing SIBO (30 50% prevalence) due to various factors, including sticky mucus blocking pancreatic ducts, altered immunological environment of the small intestine, slower intestinal motility, frequent antibiotic, and proton pump inhibitor use (1518)

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