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IL-6, another inflammatory marker reduced by tirzepatide, crosses the blood-brain barrier and directly affects neurotransmitter production
In addition, some studies have shown that GLP1R agonists can improve mortality, increased left ventricular ejection fraction, and attenuate the level of brain natriuretic peptide in the patients with type 2 diabetes and HF 13,14,15
The application of autophagy-related molecules as therapeutic targets to counteract DOR is still in its early stages and warrants additional research to clarify both their therapeutic potential and associated risks
If symptoms occur during a dose increase, consult your doctor about staying on your current dose longer before escalating
