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MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours
The mTORC2 complex consists of the mTOR kinase, mLST8, Rictor (instead of mTORC1 Raptor) mSin1, Deptor and Protor [97, 99]
Addressing and ruling these out is the first course of action, not adding more compounds
The following serious adverse events have been identified in trials or carry class-level warnings based on related drugs: Pancreatitis Acute pancreatitis has been reported with GLP-1 receptor agonists as a class
However, several practical considerations warrant careful clinical assessment
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