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Plasma concentrations are highest in childhood and decline with age, which is part of why GHK-Cu shows up frequently in skin-regeneration, wound-healing, and aging-biology research as both an endogenous reference compound and a candidate study tool in cell-based models
Clinical reports suggest broader applications
The response is dependent on temperature conditions
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This arginine-derived metabolic network includes the ureotelic nitrogen metabolites that are the primary focus of this review article: nitric oxide, polyamines, and their derivatives like polyamine-derived GABA
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