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Structure analysis thus suggests that the transporter requires GSH as a cofactor to shield the metal ion charge and thereby facilitate stable substrate binding
It works by reducing melanin production, which leads to a more even skin tone and can lighten dark spots or hyperpigmentation
However, given the known autocrine/paracrine actions of IGF-1, local manipulation of IGF-1 expression and secretion by muscle fibres may not only be safer but also more effective (Fig
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