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Many patients struggle with getting adequate protein and nutrients while eating less overall

(8) coping with pain

doi:10.23736/S2724-6507.20.03369-6 16

If you indicate you have type 2 diabetes, the projection is adjusted based on the SURMOUNT-2 and STEP-2 trial data, which showed moderately lower average weight loss in this population 3,4

More serious potential adverse effects include pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury (especially with dehydration), and increased risk of hypoglycemia when used with insulin or sulfonylureas

Recently, the SELECT trial assessed the impact of semaglutide on cardiovascular outcomes in overweight and obese patients without diabetes but with established CVD