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Patients with Hashimotos who also have unresolved gut dysbiosis including Candida often experience persistently elevated TPO antibodies despite thyroid hormone replacement

For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment

But just because you're not constantly hungry doesn't mean your body stopped needing nutrients

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To explore how well GLP-1R agonists access various parts of the brain, Sechers team labeled various agonists with fluorescent tags so that when they administered the agonists to mice, they could see which areas of their brains lit up