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PFK15, a small molecule inhibitor of PFKFB3, induces cell cycle arrest, apoptosis and inhibits invasion in gastric cancer

Their work includes chronic dosing studies extending to 6 weeks, comprehensive tissue examination at necropsy, and genetic toxicology assessment using standardized protocols accepted by regulatory agencies worldwide

At minimum, the date is essential

doi: 10.1093/brain/aww175 130 CrutchSJLehmannMSchottJMRabinoviciGDRossorMNFoxNC

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Using the common terminology criteria for adverse events (CTCAE - Version 5.0) to evaluate the severity of adverse events of anticancer therapies