Tirzepatide is technically a dual agonist GLP-1/GIP (glucose-dependent insulinotropic polypeptide) Liraglutide (Saxenda and Victoza) Each of these works in a similar way, but differs in terms of how long they stay active in the body and how they interact with different receptors
DYRK inhibitors, such as AZ Dyrk1B 33 and ID-8, increase the GLP-1 protein levels in GLUTag cells and the number of L and K cells in zebrafish and diabetic rats
Nat Rev Mol Cell Biol (2012) 13(4):25162
BRLG, MFC, DBC, HJD, and JCGG are employees of Procter & Gamble and are named as co-inventors on patents relevant to this work
Adding GIP receptor activation on top of GLP-1 pushed weight loss into a new tier
Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia