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While current methods have transformed modern therapeutics, they remain constrained by poor oral bioavailability, stability challenges, cold-chain dependence, and limited patient acceptability associated with injectable administration, according to a review in AAPS PharmSciTech

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Lahring J, Leifheit-Nestler M, Ewert A, Herzig N, Koppl C, Pott V, Oh J, Buscher A, Thumfart J, Weber LT, Arbeiter K, Acham-Roschitz B, Tonshoff B, Zivicnjak M, Hohenfellner K, Haffner D (2024) Cystinosis-associated metabolic bone disease across ages and CKD stages 15D/T

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The actions of GLP-1 are the target of Ozempic