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This is followed by preclinical studies to assess pharmacology and toxicity, along with formulation development to enhance oral bioavailability through absorption-enhancement systems

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One such agonist is L3740

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Dietary Hormesis Beyond Nutrition and Energy: A Paradigm Shift in Food Science Research The traditional paradigm in food science, centered on nutrient provision and the avoidance of toxicity, falls short in explaining the health benefits conferred by certain dietary components that act through the induction of mild biological stress responses

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