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Chronic insomnia, defined as insomnia that occurs more than three nights per week for three months, can even increase a persons risk for high blood pressure and heart disease

doi: 10.1038/nm786 102 GillisSCrabtreeGRSmithKA

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Takahashi and Mashima, 2022

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The resulting improvement in delivery precision translates directly into greater formulation stability and enhanced therapeutic efficacy (274)