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Increased apoptotic cells, including Caspase-8 and TUNEL-positive cells, were observed in the conjunctiva of DE mice [74]

The primary and secondary outcome endpoints of MACE and nonfatal stroke demonstrated significant reductions in the dulaglutide-treated REWIND trial and the subcutaneous semaglutide-treated SUSTAIN-6 study [41]

Trials aiming for glycemic equipoise should appraise the long-term effects of GLP-1 RAs on coronary events independent of glycemic control

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