Single-cell transcriptomic atlas of primate ovarian aging
The antihypertensive effects of GLP-1 RAs are due to several mechanisms: natriuretic effects, vasodilation, and reduced sympathetic activity
Oxidative stress in autism spectrum disorder
(6) L E Diamond, D C Earle, R C Rosen, et al (2004) Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction International Journal of Impotence Research, Volume 16, pages 5159 (2004)
this activates the tubulo-glomerular feedback responsible for afferent arteriole dilation and efferent arteriole constriction and, ultimately, leads to glomerular hyperfiltration and hypertension
Similarly, immune checkpoint inhibitors may result in a number of adverse side effects including autoimmunity (e.g., bullous pemphigoid, lichen planus pemphigoid, dermatomyositis, etc.)