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Consistent with this finding, we observed less respiration in response to CI and III substrates in isolated gWAT mitochondria and primary adipocytes from mice lacking adipocyte Ndufs2 (Extended Data Fig

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Additional safety concerns include hypoglycemia risk when used with insulin or insulin secretagogues, potential acute kidney injury with dehydration, and with semaglutide, worsening of diabetic retinopathy in patients with pre-existing retinopathy

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Never use a vial that has been at room temperature for more than the specified timeframe or that shows discoloration, cloudiness, or particles