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PLoS ONE 14 , e0225110 (2019)

It is a synthetic form of B12 where the B12 is attached to cyanide

Study participants receiving active treatment saw three times the weight loss experienced by those in the placebo group

Physiol Mol Biol Plants 32 , 163183 (2026)

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years

However, things like the severity of a condition and how the procedure is performed can actually affect the efficacy