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The decision to continue or discontinue GLP-1 therapy should be made with your healthcare provider based on your individual risk factors, response to treatment, and long-term health goals

List Of Sources Used In This Article American Heart Association Journals

Variants in GLP1R (the very receptor semaglutide targets), FTO (the fat-mass and obesity-associated gene), MC4R (central to satiety and energy balance), and TCF7L2 (linked to glucose homeostasis and GLP-1 secretion) map your baseline metabolic terrain

Discussing long-term treatment plans with your provider helps prevent frustrating weight regain cycles

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Jung, J.-Y