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Because mild abdominal discomfort can occur with higher doses of magnesium, it is best to gradually increase and/or divide doses during the day

This can reduce the sense of heaviness that many people describe before treatment

This decision was based on the results of the SELECT trial, which followed over 17,600 participants and found that Wegovy reduced the risk of major adverse cardiovascular events by about 20%

Tirzepatide takes it a step further by also mimicking another hormone called GIP, which works together with GLP-1 to reduce appetite and improve how your body handles food

The time varies with your natural skin tone, metabolism, and consistency of treatment

Subsequent research expanded to dual agonists like tirzepatide (GLP-1/GIP), paving the way for Retatrutide, which uniquely integrates GLP-1, GIP, and glucagon receptor activity