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For the trial product estimand, continuous endpoint analyses were conducted using a mixed model for repeated measures with randomized treatment as a factor and baseline endpoint value as a covariate

The trial data is strong and convincing, and there's already a long line of safety and efficacy evidence from people with diabetes who have taken the drug, he says

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This study is reported in accordance with ARRIVE guidelines

Blood pressure and fasting glucose readings frequently show measurable improvement by this checkpoint, even before substantial weight loss occurs

Have a higher weight with related health conditions Have struggled with weight loss through lifestyle measures alone Require improved blood sugar control alongside weight management