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Future research should prioritize the development of organ-on-chip models and multicellular co-cultures, as well as targeted preventive and therapeutic strategies (reducing iatrogenic exposure, modulating dysbiosis, antioxidants, SGLT2 inhibitors, targeting redox pathways, and the inflammatory axis)

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Exercise prescription should be prescribed and supervised by a physiotherapist

It serves as the raw material for nitric oxide synthase, the enzyme responsible for generating NO

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