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Insulin is a hormone that regulates blood glucose levels, and its deficiency or resistance leads to hyperglycemia, which can cause complications like heart disease, nerve damage, kidney failure, and vision problems
The SURMOUNT 5 trial , published in the New England Journal of Medicine in 2025, provided the first head-to-head comparison
[90] Endocrine effects may include suppression of the hypothalamic-pituitary-adrenal axis, which could lead to adrenal insufficiency if therapy is discontinued abruptly
(1997) 273:G9207
Abbass NJ, Nahlawi R, Shaia JK, et al
If you want to drink alcohol while on tirzepatide, limit your alcohol intake, avoid drinking alcohol on an empty stomach, stay hydrated, keep a track of your symptoms, and discuss with your health care provider before consuming alcohol or if you experience any side effects
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