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Thyroid dysfunction, cortisol dysregulation, and sex hormone imbalance can all silently undermine weight maintenance if left untreated

If your genetic profile shows reduced NAD synthesis capacity or mitochondrial stress markers, incorporating a modest NAD precursor supplement may support energy production and glucose handling while you're on tirzepatide

This can often be observed within the first one to two weeks of initiating a study

Today we talk with leading expert Eric Topol about two aspects of this story

That distinction targeted fat pathway versus systemic GH-axis stimulation is the core of why researchers choose one over the other, and it shapes everything from their evidence base to their regulatory status

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