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But what makes GLP-1 agonists so revolutionary

Disruptions in the NVU, leading to BBB dysfunction and reduced CBF, are early events in various neurodegenerative diseases, including AD, PD, and ALS [85]

Glutamate uptake by astrocytes is converted to glutamine by glutamine synthetase (GS)

It co-localizes with multiple hormones and neurotransmitters, suggesting broad regulatory functions

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