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Better outcomes with GLP-1s in those with diabetes and peripheral arterial disease July 29, 2026 Summary: In a propensity-matched observational study of 2,133 pairs of patients with type 2 diabetes and peripheral artery disease, those prescribed GLP-1 receptor agonists had lower five-year rates of death, hospitalization, revascularization, and amputation than those prescribed metformin

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If you are of childbearing age, effective contraception is recommended while taking these medicines, and they should be avoided during pregnancy

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10.1073/pnas.0506836103 Proc

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair