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Retrieved 16 November 2023
It should have a defensible medical purpose, an appropriate prescriber, a qualified sterile-compounding source and informed consideration of the evidence and risks
It works intracellularly by inhibiting NNMT to preserve NAD+ and shift adipocyte metabolism a completely different mechanism, with different research read-outs
It decreases basal corticotropin levels and blocks cortisol release, which explains its stress-reducing properties
There is a gradient of reactive morphotypes, with the most reactive cells (border-forming astrocytes and amoeboid microglia) concentrating at the lesion perimeter, or even entering (reactive microglia) the lesion core
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