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Third, the 2-4% weight loss difference (if confirmed) may be statistically significant in studies but have little practical meaning for specific individuals

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This creates a clinical dilemma during pregnancy and preconception care, as safety data have historically been limited due to the systematic exclusion of pregnant women from randomized controlled trials

The authors also validated that GSH content and GPX4 activity were significantly decreased when H22 cells were co-incubated with Mn-MOF (Figures 5H, I)