(This information should not be considered a substitute for professional medical advice, diagnosis or treatment.) The Best Online GLP-1 Services: How to Sign Up Most (if not all) of the best telehealth sites that offer GLP-1 meds will have you take a 2- to 5-minute quiz to assess your health, medical history, weight loss goals and other personal and clinical factors
Semaglutide, at least, only works in the one direction
Originally developed for type 2 diabetes management, Semaglutide gained widespread attention after the STEP 1 clinical trial (NEJM, 2021) demonstrated an average weight loss of 14.9% of body weight over 68 weeks at the 2.4mg weekly dose
As Morgan Stewart, PharmD from the University of Texas at Austin, notes: "Tirzepatide sometimes causes more side effects than semaglutide because it works on two hormones instead of one." Additionally, Tirzepatide has yet to receive FDA approval for cardiovascular benefits, which are still under study
Qsymia or generic phentermine-topiramate may be the pragmatic choice
For instance, younger adults and people with higher baseline weights experienced greater changes