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The majority (67%) had Crohns disease (CD) and on advanced therapy (86%)

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Multi-layer integration (transcriptomic endotyping, immune phenotyping, and uterine fluid proteomics/metabolomics) is therefore valuable not because it adds more markers, but because it can help discriminate timing misalignment from intrinsic dysfunction and connect molecular programs to patient-relevant outcomes [448, 449]

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However, the protocol for a missed dose remains largely the same, as the active ingredient functions similarly