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Contact your healthcare provider if you experience minimal improvement after reaching maintenance dose for 12-16 weeks, including persistently elevated blood glucose or lack of at least 5% body weight reduction

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Methylation levels of SFRP1 , SFRP2 , SDC2 , and PRIMA1 were determined using a MethyLight assay after cfDNA isolation and bisulfite conversion of samples ( SOX21 gene promoter methylation, serving as a fecal-based noninvasive biomarker for early diagnosis of colorectal cancer (Moradi et al., 2021)

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For other concerns about your treatment, contact your GP or prescribing clinician promptly