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These studies indicate that the cytopathic effects observed during HSV-1 encephalitis may not be simply due to viral replication, but may result from additional host-mediated secondary mechanisms involving the over activation of microglial cells

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Membranes were then probed with horseradish peroxidase-conjugated secondary antibodies antirabbit IgG (Abcam, A16035, 1:5,000) or antimouse IgG (Abcam, A16011, 1:5,000) and developed using enhanced chemiluminescence substrate (Bio-Rad, 170-5060)

Conditions that impair liver function reduce glutathione: Non-alcoholic fatty liver disease (NAFLD) Alcohol-related liver disease Hepatitis Medication-induced liver stress (acetaminophen, statins) 5

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