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Being able to maintain a calorie-deficient diet is the key to losing weight, as fewer calories being consumed forces the body to break down the stored excess fat deposits to use as energy when there isnt enough energy being consumed

A dedicated sub study in patients with type 2 diabetes, published in The Lancet Diabetes & Endocrinology , confirmed this picture: gastrointestinal side effects were the most common adverse events, but no deaths were reported during the trial period

The dietary supplement should not be used as a substitute (replacement) for various food products

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Results: Berberine ameliorates glucose metabolism in db/db mice