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Secondary outcomes included MACEs (cardiovascular death, ischemic stroke, or myocardial infarction), all-cause mortality, and progression to long-term dialysis
The same principle applies when switching between semaglutide and tirzepatide , though that requires dose recalculation since the medications are not milligram-equivalent
Building on this success, the field has progressed toward dual and triple agonists to further enhance metabolic outcomes, exemplified by GLP-1/GIP co-agonists that deliver superior glycemic and weight control 1
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Compounded semaglutide absolutely expires