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Ces symptmes ne sont gnralement pas spcifiques, mais lorsquils apparaissent ensemble, ils peuvent devenir perceptibles

MR is strongly recommended as a means of prioritizing drug targets for cardiovascular research, to avoid expensive failures in phase III randomized controlled trials (RCTs) [18, 19] and to identify mechanistic targets of intervention, complementary to RCTs [19]

On the other side, methylglyoxal-induced p53 might restrain tumorigenesis, at least in human endothelial cells [199]

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implication in humans is still under investigation, so some GLP1 drugs carry warnings (especially for those with a medullary thyroid carcinoma history)