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In June 2023, the American Society of Anesthesiologists issued guidance advising patients to skip daily weight-loss medications on the day of surgery and hold off on weekly injections for a week before any sedation procedures

These actions are thought to be primarily mediated through central brain populations of GLP-1 receptors

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After about 68 weeks of use, many users lost at least 15% of their starting body weight, while nearly a third lost 20% or more, according to clinical studies

Koopman, J

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